FEATURES OF THE COURSE OF DYSENTERY WITH ACUTE RESPIRATORY INFECTIONS

Abstract

Acute intestinal infections (AKI) are a significant problem of children's health. The combined course of acute respiratory viral infections and acute respiratory viral infections (ARVI) is a common phenomenon, potentially aggravating the course of acute respiratory viral infections. This study is aimed at studying the features of the clinical course of dysentery in association with acute respiratory viral infections in children. The purpose of the study. To study the clinical features of dysentery associated with acute respiratory viral diseases in children. Materials and methods. A prospective clinical follow-up was conducted for 50 children under the age of 7 years with a confirmed diagnosis of dysentery complicated by acute respiratory viral infections. The etiological structure of ARVI was assessed by PCR diagnostics, as well as adenovirus serotyping. The results and their discussions. Compared with the control group, children with co-infection had significantly longer duration of diarrhea (7.2 ± 2.1 days vs. 5.5 ± 1.8 days, p<0.05), higher levels of C-reactive protein (45 ± 15 mg/l vs. 25 ± 10 mg/l, p<0.01) and a tendency to more frequent release of E. coli (46% vs. 70%, p=0.06). An increase in the duration of diarrhea and an increase in CRP levels in children with co-infection indicates a more pronounced inflammatory process in the intestine, which may be due to the synergistic effect of bacterial and viral infections. The tendency towards less frequent shigella release requires further study of the mechanisms of virus influence on bacterial colonization. Conclusions. Thus, acute respiratory infections of viral etiology often accompany dysentery, and dysentery in such cases usually occurs in severe and moderate forms. Moreover, the younger the child, the more severe the disease is, especially in young children, often leading to death.